|
Plant Cell, Vol. 11, 1935-1944, October 1999, Copyright © 1999, American Society of Plant Physiologists
Anticipating Endoplasmic Reticulum Stress: A Novel Early Response before Pathogenesis-Related Gene Induction
Edith P. W. M. Jelitto-Van Doorena,
Sabina Vidalb, and
Jürgen Deneckea
a Leeds Institute for Plant Biotechnology and Agriculture (LIBA), School of Biology, University of Leeds, Leeds LS2 9JT, United Kingdom
b Department of Plant Biology, Swedish University of Agricultural Sciences, Box 7070, S-750 07 Uppsala, Sweden
Correspondence to:
Jürgen Denecke, j.denecke{at}leeds.ac.uk (E-mail), 44-113-233-2835 (fax)
When it is attacked by a pathogen, a plant produces a range of defense-related proteins. Many of these are synthesized by the rough endoplasmic reticulum (RER) to be secreted from the cell or deposited in vacuoles. Genes encoding endoplasmic reticulum (ER)–resident chaperones, such as the lumenal binding protein (BiP), are also induced under these conditions. Here, we show that BiP induction occurs systemically throughout the plant. Furthermore, this induction occurs rapidly and precedes expression of genes encoding pathogenesis-related (PR) proteins. The underlying signal transduction pathway was shown to be independent of the signaling molecule salicylic acid and the unfolded protein response pathway. In addition, BiP induction was independent of PR gene induction. Overproduction of BiP alone was not sufficient to cause induction of PR gene expression; however, limiting the amount of BiP in the ER lumen via superimposed ER stress inhibited the induction of PR gene expression. We propose that the induction of BiP expression during plant–pathogen interactions is required as an early response to support PR protein synthesis on the RER and that a novel signal transduction pathway exists to trigger this rapid response.
This article has been cited by other articles:
|
|
|
|
 
K. G. Zulak, M. F. Khan, J. Alcantara, D. C. Schriemer, and P. J. Facchini
Plant Defense Responses in Opium Poppy Cell Cultures Revealed by Liquid Chromatography-Tandem Mass Spectrometry Proteomics
Mol. Cell. Proteomics,
January 1, 2009;
8(1):
86 - 98.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Watanabe and E. Lam
BAX Inhibitor-1 Modulates Endoplasmic Reticulum Stress-mediated Programmed Cell Death in Arabidopsis
J. Biol. Chem.,
February 8, 2008;
283(6):
3200 - 3210.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J.-X. Liu, R. Srivastava, P. Che, and S. H. Howell
An Endoplasmic Reticulum Stress Response in Arabidopsis Is Mediated by Proteolytic Processing and Nuclear Relocation of a Membrane-Associated Transcription Factor, bZIP28
PLANT CELL,
December 1, 2007;
19(12):
4111 - 4119.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Wang, S. Narendra, and N. Fedoroff
Heterotrimeric G protein signaling in the Arabidopsis unfolded protein response
PNAS,
March 6, 2007;
104(10):
3817 - 3822.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. FEDOROFF
Redox Regulatory Mechanisms in Cellular Stress Responses
Ann. Bot.,
August 1, 2006;
98(2):
289 - 300.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Chivasa, J. M Hamilton, R. S Pringle, B. K Ndimba, W. J Simon, K. Lindsey, and A. R Slabas
Proteomic analysis of differentially expressed proteins in fungal elicitor-treated Arabidopsis cell cultures
J. Exp. Bot.,
April 1, 2006;
57(7):
1553 - 1562.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Pimpl, J. P. Taylor, C. Snowden, S. Hillmer, D. G. Robinson, and J. Denecke
Golgi-Mediated Vacuolar Sorting of the Endoplasmic Reticulum Chaperone BiP May Play an Active Role in Quality Control within the Secretory Pathway
PLANT CELL,
January 1, 2006;
18(1):
198 - 211.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Wang, N. D. Weaver, M. Kesarwani, and X. Dong
Induction of Protein Secretory Pathway Is Required for Systemic Acquired Resistance
Science,
May 13, 2005;
308(5724):
1036 - 1040.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Iwata and N. Koizumi
An Arabidopsis transcription factor, AtbZIP60, regulates the endoplasmic reticulum stress response in a manner unique to plants
PNAS,
April 5, 2005;
102(14):
5280 - 5285.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Muller, P. Piffanelli, A. Devoto, M. Miklis, C. Elliott, B. Ortmann, P. Schulze-Lefert, and R. Panstruga
Conserved ERAD-Like Quality Control of a Plant Polytopic Membrane Protein
PLANT CELL,
January 1, 2005;
17(1):
149 - 163.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Vitale and A. Ceriotti
Protein Quality Control Mechanisms and Protein Storage in the Endoplasmic Reticulum. A Conflict of Interests?
Plant Physiology,
November 1, 2004;
136(3):
3420 - 3426.
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Wick, X. Gansel, C. Oulevey, V. Page, I. Studer, M. Durst, and L. Sticher
The Expression of the t-SNARE AtSNAP33 Is Induced by Pathogens and Mechanical Stimulation
Plant Physiology,
May 1, 2003;
132(1):
343 - 351.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Matsushima, Y. Hayashi, M. Kondo, T. Shimada, M. Nishimura, and I. Hara-Nishimura
An Endoplasmic Reticulum-Derived Structure That Is Induced under Stress Conditions in Arabidopsis
Plant Physiology,
December 1, 2002;
130(4):
1807 - 1814.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. E. Carette, K. Guhl, J. Wellink, and A. Van Kammen
Coalescence of the Sites of Cowpea Mosaic Virus RNA Replication into a Cytopathic Structure
J. Virol.,
May 13, 2002;
76(12):
6235 - 6243.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Hermsmeier, U. Schittko, and I. T. Baldwin
Molecular Interactions between the Specialist Herbivore Manduca sexta (Lepidoptera, Sphingidae) and Its Natural Host Nicotiana attenuata. I. Large-Scale Changes in the Accumulation of Growth- and Defense-Related Plant mRNAs
Plant Physiology,
February 1, 2001;
125(2):
683 - 700.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
A. Vitale and G. Galili
The Endomembrane System and the Problem of Protein Sorting
Plant Physiology,
January 1, 2001;
125(1):
115 - 118.
[Full Text]
|
|
|
|
|
